Spirulina: The Aztec superfood!

Spirulina was a dietary staple of the Aztec people of pre-Hispanic Mexico which they harvested from the surface of Lake Texcoco. Aztec couriers and runners in ancient Tenochtitlan would eat dried spirulina cakes with corn, tortillas, beans and chillies as fuel for long journeys [1].

Spirulina is high in protein and contains a range of vitamins including B12 and provitamin A (beta-carotene), along with iron and other minerals. This Aztec superfood is high in phenolic acids, tocopherols and γ-linolenic acid [2]. Because spirulina lacks cellulose cell walls it is very easily digested [2].

In addition to its nutritional value, spirulina helps control inflammation, cholesterol and may even help prevent cancer.

The Anti-inflammatory properties of Spirulina

It is well documented that Spirulina exhibits anti-inflammatory properties [3],[4] and medical trials show that it has a strong protective effect against allergic rhinitis (hay fever and similar allergies) [5], [6],[7]. In a recent double-blind, placebo-controlled study, Spirulina consumption significantly improved the symptoms of allergic rhinitis, including nasal discharge, sneezing, nasal congestion and itching [8]. These studies indicate that Spirulina may help support effective function of the immune system by covering nutritional deficiencies.

Spirulina and a healthy heart

Nakaya et al. [9], gave 4.2 g day−1 of Spirulina to 15 male volunteers and observed a significant reduction of high-density lipoprotein (LDL) cholesterol after 8 weeks of treatment. The atherogenic (artery plaque forming) effect also declined significantly [9]. Ramamoorthy and Premakumari [10] trialled Spirulina supplements in ischemic heart disease patients and found a significant reduction in blood cholesterol, triglycerides and LDL cholesterol and an increase in HDL cholesterol. Finally, Mani et al. [11] in a clinical study, found a significant reduction in LDL : HDL ratio in a number of diabetic patients who were given Spirulina.

Spirulina and Cancer

It is possible that the combined antioxidant and immune modulation characteristics of Spirulina may assist in the destruction of tumours and therefore play a role in cancer prevention [12]. Trials on hamsters showed tumour regression after topical application or enteral intake of Spirulina extract [13–15]. A study conducted by Mathew et al. [16] on a cohort of 77 patients reported that 45% of their study cohort showed complete regression of leukoplakia after taking Spirulina supplements for 1 year. Whilst the results appear promising, it was an unblinded, non-randomized trial and as such cannot be regarded as evidence of a positive effect.

Disclaimer

Aztec Health is not liable for any information provided on this site with regard to recommendations regarding supplements for any health purposes. The information above is gathered from publicly available research and is displayed here for informational purposes. Details of the sources of this information are given below.

References

1. https://www.bbc.com/travel/article/20210111-how-mexico-is-reclaiming-spirulina
2. Dillon JC, Phuc AP, Dubacq JP. Nutritional value of the alga Spirulina. World Review of Nutrition and Dietetics. 1995;77:32–46. [PubMed] [Google Scholar]
3. Yang H-N, Lee E-H, Kim H-M. Spirulina platensis inhibits anaphaylactic reaction. Life Sciences. 1997;61(13):1237–1244. [PubMed] [Google Scholar]
4. Kim H-M, Lee E-H, Cho H-H, Moon Y-H. Inhibitory effect of mast cell-mediated immediate-type allergic reactions in rats by Spirulina . Biochemical Pharmacology. 1998;55(7):1071–1076. [PubMed] [Google Scholar]
5. Mao TK, van de Water J, Gershwin ME. Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. Journal of Medicinal Food. 2005;8(1):27–30. [PubMed] [Google Scholar]
6. Ishii K, Katoch T, Okuwaki Y, Hayashi O. Influence of dietary Spirulina platensis on IgA level in human saliva. Journal of Kagawa Nutrition University. 1999;30:27–33. [Google Scholar]
7. Hirahashi T, Matsumoto M, Hazeki K, Saeki Y, Ui M, Seya T. Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis . International Immunopharmacology. 2002;2(4):423–434. [PubMed] [Google Scholar]
8. Cingi C, Conk-Dalay M, Cakli H, Bal C. The effects of spirulina on allergic rhinitis. European Archives of Oto-Rhino-Laryngology. In press. [PubMed] [Google Scholar]
9. Nakaya N, Homa Y, Goto Y. Cholesterol lowering effect of Spirulina . Atherosclerosis. 1988;37:1329–1337. [Google Scholar]
10. Ramamoorthy A, Premakumari S. Effect of supplementation of Spirulina on hypercholesterolemic patients. Journal of Food Science and Technology. 1996;33(2):124–128. [Google Scholar]
11. Mani UV, Desai S, Iyer U. Studies on the long-term effect of Spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. Journal of Nutraceuticals, Functional and Medical Foods. 2000;2(3):25–32.[Google Scholar]
12. Karkos PD, Leong SC, Karkos CD, Sivaji N, Assimakopoulos DA. Spirulina in clinical practice: evidence-based human applications. Evid Based Complement Alternat Med. 2011;2011:531053. doi: 10.1093/ecam/nen058. Epub 2010 Oct 19. PMID: 18955364; PMCID: PMC3136577.
13. Shklar G, Schwartz J. Tumor necrosis factor in experimental cancer regression with alphatocopherol, beta-carotene, canthaxanthin and algae extract. European Journal of Cancer and Clinical Oncology. 1988;24(5):839–850. [PubMed] [Google Scholar]
14. Schwartz J, Shklar G, Reid S, Trickler D. Prevention of experimental oral cancer by extracts of Spirulina-Dunaliella algae. Nutrition and Cancer. 1988;11(2):127–134. [PubMed] [Google Scholar]
15. Schwartz J, Shklar G. Regression of experimental hamster cancer by beta carotene and algae extracts. Journal of Oral and Maxillofacial Surgery. 1987;45(6):510–515. [PubMed] [Google Scholar]
16. Mathew B, Sankaranarayanan R, Nair PP, et al. Evaluation of chemoprevention of oral cancer with Spirulina fusiformis. Nutrition and Cancer. 1995;24(2):197–202. [PubMed] [Google Scholar]